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Hydrocortisone topical

CORTIZONE-10

What it isTopical glucocorticoid and mineralocorticoid agonist; mild eczema, dermatitis, and inflammatory itching.

Why this oneIts low potency and OTC availability make it the topical steroid of choice for thin skin and sensitive sites.

What limits itProlonged, occluded, or extensive use causes skin atrophy and can suppress the adrenal axis; infection may be masked.

FDA label

FDA dosingPopulationStartTargetMax
Temporary relief of itching from minor skin irritations, inflammation, and rashes (eczema, psoriasis, seborrheic dermatitis, insect bites, poison ivy/oak/sumac, soaps, detergents, cosmetics, jewelry)Adults & children ≥2 yrApply a thin layer to the affected areaApply a thin layer to the affected area3–4 times daily

Renal Undefined

Hepatic Undefined

Instructions

Contraindications

Cautions

Adverse reactions

Pregnancy Undefined

Lactation Undefined

NO BOXED WARNINGS

Classes and tags

Clinical profile

Direct muscarinic antagonism0 / 4

Mechanism of action: Hydrocortisone topical ballicule

Hydrocortisone topical ballicule: receptor binding, kinetics and half-life diagram

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