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Guanabenz

WYTENSIN

What it isCentral alpha-2 agonist; hypertension.

Why this oneA clonidine-like agent retained where clonidine is not tolerated.

What limits itRebound hypertension on withdrawal, sedation and dry mouth. Now rarely used.

FDA-approved for

NO BOXED WARNINGS

Principal riskRebound hypertension on withdrawal, sedation and dry mouth

Classes and tags

Clinical profile

Direct muscarinic antagonism0 / 4

Mechanism of action: Guanabenz ballicule

Guanabenz ballicule: receptor binding, kinetics and half-life diagram

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