Fenoldopam
CORLOPAM
“Finn, old, with Coral”
What it isPeripheral dopamine D1-receptor agonist; short-term IV treatment of severe hypertension.
Why this oneLowers blood pressure while increasing renal blood flow, a distinctive feature among parenteral antihypertensives.
What limits itReflex tachycardia and increased intraocular pressure limit use; the infusion contains sulfite.
FDA-approved for
- severe hypertension (1997)
NO BOXED WARNINGS
Principal riskReflex tachycardia; raised intraocular pressure
Classes and tags
Clinical profile
Legacy pregnancy categoryB
Defining liabilityRapid hypotension, reflex tachycardia and hypokalemia during infusion
Open Fenoldopam in the interactive console ↗
Self-check
- What happens to renal blood flow as fenoldopam lowers BP?
It increases. - Which eye pressure can fenoldopam raise?
Intraocular pressure.