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Estriol

E3

What it isE3 — the weakest of the three classical estrogens, made in quantity by the placenta.

Why it mattersIt is the estrogen of pregnancy: maternal serum estriol reflects fetoplacental function, which gave it a role in antenatal screening.

What it changesIts weak receptor activity outside pregnancy leaves it a minor player pharmacologically in the U.S.

NO BOXED WARNINGS

Classes and tags

Clinical profile

Direct muscarinic antagonism0 / 4

Mechanism of action: Estriol ballicule

Estriol ballicule: receptor binding, kinetics and half-life diagram

Open Estriol in the interactive console ↗