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Eprosartan

TEVETEN

Pronunciation: ep-roe-SAR-tan

Eprosartan ballicule: receptor binding, kinetics and half-life diagram
Mechanism of action: Eprosartan ballicule

What it isAngiotensin II receptor blocker; hypertension.

Why this oneAlso blocks presynaptic AT1 receptors, giving some sympathoinhibition the other ARBs lack.

What limits itWeaker blood-pressure effect than the newer ARBs. Contraindicated in pregnancy.

Eprosartan molecular structure (skeletal formula)
Molecular structure: Eprosartan

Eprosartan prescription history

Animated chart of estimated U.S. prescriptions per year, RAAS inhibitors (1981–2026). Eprosartan enters in 1998 (estimated).

FDA-approved for

⚠ BOXED WARNING

Principal riskWeaker blood-pressure effect than the newer ARBs

Classes and tags

Clinical profile

Therapeutic safety burden2 / 4
Overdose danger2 / 4
Weight-gain liability0 / 4
Sedation liability1 / 4
QT / Torsades0 / 4
Direct muscarinic antagonism0 / 4
Embryofetal risk4 / 4

Legacy pregnancy categoryD

Defining liabilityFetal renal toxicity, hyperkalemia and renal dysfunction

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