Domoic acid
ASP toxin
What it isKainate receptor agonist shellfish toxin causing amnesic shellfish poisoning.
Why this oneIt demonstrated that kainate-receptor excitotoxicity can selectively destroy hippocampal neurons in humans.
What limits itNo therapeutic use; permanent anterograde amnesia in survivors.
NO BOXED WARNINGS
Principal riskA toxin with no therapeutic use
Classes and tags
Clinical profile
Mechanism of action: Domoic acid ballicule
