(Desmethyl-) mirtazapine
mirtazapine metabolite
What it isN-desmethyl metabolite of mirtazapine, roughly a tenth as potent.
Why it mattersLittle contribution, explaining mirtazapine’s predictability.
What it changesIts presence does not alter the sedation-versus-noradrenergic balance that governs mirtazapine dosing.
Used for
- depression (metabolite of mirtazapine)
NO BOXED WARNINGS
Principal riskLittle in its own right; see the parent drug
Classes and tags
Open (Desmethyl-) mirtazapine in the interactive console ↗
Self-check
- How potent is desmethylmirtazapine relative to mirtazapine?
Roughly one tenth. - Does it alter mirtazapine’s sedation–noradrenergic balance?
No.