Clonidine ER
KAPVAY
What it isClonidine ER (KAPVAY, 2010) is a central alpha-2 agonist reducing sympathetic output; nonstimulant ADHD treatment, approved ages: 6-17.
Why this oneDuration of action 12-16 h (Carlat Table 1); it is more sedating and blood-pressure lowering than guanfacine ER, which can help when insomnia accompanies ADHD.
What limits itSomnolence, bradycardia and hypotension limit use; titrate weekly, avoid abrupt stop to prevent rebound hypertension.
FDA-approved for
- ADHD (2010)
NO BOXED WARNINGS
Principal riskRebound hypertension on abrupt withdrawal
Classes and tags
Clinical profile
Mechanism of action: Clonidine ER ballicule
Open Clonidine ER in the interactive console ↗
Memory aids: mascots and interaction avatars
orange plus signs → alpha-2 agonist
