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Calcium carbonate

TUMS

What it isCalcium salt acting as an antacid and supplement.

Why this oneCheapest calcium source and best absorbed with food, and it doubles as an antacid and phosphate binder.

What limits itIt needs gastric acid, so citrate is preferred on a PPI. Constipation; it binds levothyroxine and quinolones.

FDA-approved for

FDA label

FDA dosingPopulationStartTargetMax
Acid indigestion / heartburn (OTC antacid)Adults & children ≥12 yChew 2–4 tablets PRN as symptoms occurChew 2–4 tablets PRN as symptoms occurNot stated on label

Renal Undefined

Hepatic Undefined

Instructions

Pregnancy Undefined

Lactation Undefined

NO BOXED WARNINGS

Principal riskConstipation; binds other drugs in the gut

Classes and tags

Clinical profile

Direct muscarinic antagonism0 / 4

Mechanism of action: Calcium carbonate ballicule

Calcium carbonate ballicule: receptor binding, kinetics and half-life diagram

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