Not available in the U.S.
Mechanism of action: Betahistine ballicule
Visual mnemonic: Betahistine mascot
“Bettor hissing”
Legos → theme for H3 antihistamine
What it isH3 antagonist and weak H1 agonist; Meniere disease.
Why this oneStandard therapy for Meniere vertigo across Europe and Canada.
What limits itLarge randomized trial found no benefit over placebo. Not US-approved.
Molecular structure: Betahistine
Used for
- Meniere disease (approved in Europe and Canada)
Principal riskA large randomized trial found no benefit over placebo
Classes and tags
Clinical profile
Therapeutic safety burden1 / 4
Overdose danger1 / 4
Sedation liability0 / 4
Direct muscarinic antagonism0 / 4
Embryofetal risk2 / 4
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Self-check
- What did a large randomized betahistine trial find?
No benefit over placebo. - Is betahistine US-approved?
No.