Benzoyl peroxide

PANOXYL

What it isTopical oxidizing agent that disrupts bacterial membranes; acne vulgaris.

Why this oneIt kills acne bacteria without selecting antibiotic resistance, making it a key partner for topical antibiotics.

What limits itDryness and irritation often limit adherence; it bleaches hair and fabric, and rare hypersensitivity can be severe.

FDA label

FDA dosing	Population	Start	Target	Max
Acne (OTC topical)	General (OTC; no age stated on captured label)	Thin layer to entire affected area QD	Gradually increase to BID–TID if needed or as directed by a doctor	TID

Renal Undefined

Hepatic Undefined

Excessive skin drying may occur — start QD and increase gradually

Clean skin thoroughly before applying
Apply thin layer covering entire affected area
If bothersome dryness or peeling: reduce to QD or every other day
If going outside, apply sunscreen after use; if irritation or sensitivity develops, stop both products and ask a doctor

Excessive drying of the skin may occur — titrate frequency to tolerance
Sun exposure: apply sunscreen after use; discontinue both if irritation or sensitivity develops

Pregnancy Undefined

Lactation Undefined

NO BOXED WARNINGS

Direct muscarinic antagonism0 / 4