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Benazeprilat

from benazepril

What it isThe active metabolite of benazepril — the diacid that actually inhibits ACE.

Why it mattersBenazepril is an ester prodrug; essentially all of its effect is this molecule, generated by hepatic esterases.

What it changesIts renal clearance, not the parent’s, is what accumulates in kidney disease and drives dose adjustment.

NO BOXED WARNINGS

Classes and tags

Clinical profile

Direct muscarinic antagonism0 / 4

Mechanism of action: Benazeprilat ballicule

Benazeprilat ballicule: receptor binding, kinetics and half-life diagram

Open Benazeprilat in the interactive console ↗