Not available in the U.S.
Mechanism of action: Aprindine ballicule
What it isClass I antiarrhythmic; arrhythmias.
Why this oneRetained in some markets for refractory arrhythmia.
What limits itAgranulocytosis and hepatotoxicity; now rarely used. Not US-approved.
Molecular structure: Aprindine
Used for
- cardiac arrhythmias (non-US)
- arrhythmias (approved in Japan)
Principal riskAgranulocytosis and hepatotoxicity; now rarely used
Classes and tags
Clinical profile
Therapeutic safety burden3 / 4
Sedation liability1 / 4
Direct muscarinic antagonism0 / 4
Embryofetal risk4 / 4
Open Aprindine in the interactive console ↗
Self-check
- What blood toxicity limits aprindine?
Agranulocytosis. - Is aprindine US-approved?
No.