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Al/Mg antacid

MAALOX / MYLANTA

What it isA combination antacid pairing aluminum hydroxide with magnesium hydroxide to neutralize gastric acid.

Why this oneCombining the two balances aluminum's constipating effect against magnesium's laxative effect for better GI tolerability than either alone.

What limits itLike other polyvalent-cation antacids it binds fluoroquinolones, tetracyclines, and other drugs, and both cations can accumulate dangerously in renal impairment.

FDA label

FDA dosingPopulationStartTargetMax
Antacid / antigas (per Drug Facts Purpose)Adults and children >=12 y2-4 tsp (10-20 mL) QID, or as directed by a physician2-4 tsp (10-20 mL) QID16 tsp (80 mL)/24 h; do not use maximum dosage >2 weeks
Antacid / antigas (per Drug Facts Purpose)Children <12 yConsult a physicianConsult a physicianNot stated

Renal Ask a doctor before use if you have kidney disease (OTC label; no dose adjustment given)

Hepatic Undefined

Do not exceed 16 teaspoonfuls in 24 h, or use the maximum dosage for more than 2 weeks, except under physician supervision

Instructions

Cautions

Pregnancy Undefined

Lactation Undefined

NO BOXED WARNINGS

Principal riskNo FDA boxed warning.

Classes and tags

Clinical profile

Direct muscarinic antagonism0 / 4

Mechanism of action: Al/Mg antacid ballicule

Al/Mg antacid ballicule: receptor binding, kinetics and half-life diagram

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