Ballicules.com

Aldosterone

endogenous

What it isThe endogenous mineralocorticoid driving sodium retention and potassium excretion.

Why this oneIt is the target of spironolactone, eplerenone and finerenone, and the reason those drugs cause hyperkalemia.

What limits itIts escape from ACE-inhibitor suppression is why an MRA is added in heart failure rather than relying on RAAS blockade alone.

NO BOXED WARNINGS

Principal riskEndogenous or dietary; no boxed warning applies

Classes and tags

Clinical profile

Direct muscarinic antagonism0 / 4

Mechanism of action: Aldosterone ballicule

Aldosterone ballicule: receptor binding, kinetics and half-life diagram

Open Aldosterone in the interactive console ↗

Memory aids: mascots and interaction avatars

Aldosterone endogenous mascot mnemonic cartoon
“Al-Dough stir own”
bananas dispersing → decreased serum potassium
retention of whater and sodium

Open Aldosterone in the interactive console ↗