MATE2-K inhibitor
- Inhibits MATE2-K
- Can change exposure of transporter substrates
- Direction depends on uptake vs efflux location
- Clinically important for selected narrow-index drugs
Interaction at a glance
Mechanism
Magnitude / time course
- Can change exposure of transporter substrates
Mechanism / modifiers
- Direction depends on uptake vs efflux location
- Clinically important for selected narrow-index drugs
Self-check
- What does “MATE2-K inhibitor” mean?
Inhibits MATE2-K.
Drugs in this interaction (3)
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