MAO-B substrate
- Metabolized by monoamine oxidase B
- MAO-B inhibition can reduce substrate breakdown
- Brain monoamine handling may be affected
- Clinical importance is substrate-specific
- Other clearance pathways often contribute
Interaction at a glance
- Metabolized by monoamine oxidase B
Management
- Metabolized by monoamine oxidase B
- MAO-B inhibition can reduce substrate breakdown
Mechanism
- Brain monoamine handling may be affected
Magnitude / time course
- Clinical importance is substrate-specific
- Other clearance pathways often contribute
Self-check
- What can MAO-B inhibition do to substrate breakdown?
It can reduce breakdown. - Do other clearance pathways often contribute for MAO-B substrates?
Yes.
Drugs in this interaction (2)
All interaction examples · Open MAO-B substrate in the interactive console ↗