Vitamin D and analogs
- Activate vitamin-D receptor signaling
- Increase intestinal Ca/phosphate handling
- Treat deficiency and selected CKD/bone disorders
- Calcitriol is the active hormone
- Analogs can suppress PTH
- Excess causes hypercalcemia/hyperphosphatemia
Class at a glance
- Activate vitamin-D receptor signaling
Clinical role
- Increase intestinal Ca/phosphate handling
- Treat deficiency and selected CKD/bone disorders
Members / distinctions
- Calcitriol is the active hormone
- Analogs can suppress PTH
Practical pearls
- Excess causes hypercalcemia/hyperphosphatemia
Self-check
- What can excess vitamin-D activity cause?
Hypercalcemia and hyperphosphatemia.
- Which vitamin-D form is the active hormone?
Calcitriol.
Drugs in this class (7)
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