Skeletal muscle relaxants
- Heterogeneous drugs for spasm/spasticity
- Many act centrally and are sedating
- Baclofen/tizanidine target spasticity
- Cyclobenzaprine-type drugs target acute spasm
- Evidence for chronic nonspecific pain is limited
- Falls/CNS-depressant combinations are concerns
Class at a glance
- Heterogeneous drugs for spasm/spasticity
Practical pearls
- Baclofen/tizanidine target spasticity
Clinical role
- Cyclobenzaprine-type drugs target acute spasm
- Evidence for chronic nonspecific pain is limited
Safety / monitoring
- Many act centrally and are sedating
- Falls/CNS-depressant combinations are concerns
Drugs in this class (9)
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