Potassium binders

Remove K+ through the GI tract
Patiromer + sodium zirconium cyclosilicate
Best for chronic/subacute hyperkalemia control
Not substitutes for IV calcium in emergencies
Patiromer can bind other oral drugs
SZC can cause sodium-related edema
Help preserve RAAS/MRA therapy when K rises

Class at a glance

Remove K+ through the GI tract

Practical pearls

Patiromer can bind other oral drugs

Members / distinctions

Patiromer + sodium zirconium cyclosilicate
Not substitutes for IV calcium in emergencies
SZC can cause sodium-related edema
Help preserve RAAS/MRA therapy when K rises

Safety / monitoring

Best for chronic/subacute hyperkalemia control

Self-check

What important adverse effect is associated with SZC?
sodium-related edema.

Drugs in this class (3)

Patiromer ballicule — decagon mechanism diagram — Patiromer

Sodium zirconium cyclosilicate ballicule — decagon mechanism diagram — Sodium zirconium cyclosilicate

Sodium polystyrene sulfonate ballicule — decagon mechanism diagram — Sodium polystyrene sulfonate

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