Mineralocorticoids
- Activate mineralocorticoid receptors
- Promote renal Na+ retention and K+ loss
- Fludrocortisone is the main therapeutic drug
- Used in adrenal insufficiency + selected orthostasis
- Can cause HTN, edema + hypokalemia
- Not equivalent to glucocorticoid replacement
Class at a glance
- Activate mineralocorticoid receptors
Practical pearls
- Fludrocortisone is the main therapeutic drug
Clinical role
- Can cause HTN, edema + hypokalemia
- Not equivalent to glucocorticoid replacement
Clinical role / physiology
- Promote renal Na+ retention and K+ loss
- Used in adrenal insufficiency + selected orthostasis
Drugs in this class (2)
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