Mast-cell stabilizers
- Reduce mast-cell mediator release
- Cromolyn/ketotifen are classic examples
- Preventive—not rescue—therapy
- Used in selected allergy/asthma settings
- Local formulations minimize systemic effects
- Generally modest efficacy but favorable safety
Class at a glance
- Reduce mast-cell mediator release
Practical pearls
- Cromolyn/ketotifen are classic examples
Clinical role
- Preventive—not rescue—therapy
- Used in selected allergy/asthma settings
Members / distinctions
- Local formulations minimize systemic effects
- Generally modest efficacy but favorable safety
Self-check
- What do Mast-cell stabilizers primarily reduce?
mast-cell mediator release.
Drugs in this class (2)
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