Fluoroquinolones
- Broad oral/IV DNA-gyrase inhibitors
- Excellent tissue penetration
- Useful for selected UTI, GI + respiratory disease
- Tendon rupture, neuropathy + CNS toxicity
- QT prolongation varies by agent
- Dysglycemia + aortic warnings matter
- Avoid when safer effective alternatives exist
Class at a glance
- Broad oral/IV DNA-gyrase inhibitors
Safety / monitoring
- QT prolongation varies by agent
Clinical role
- Excellent tissue penetration
- Useful for selected UTI, GI + respiratory disease
Safety distinctions
- Tendon rupture, neuropathy + CNS toxicity
- Dysglycemia + aortic warnings matter
- Avoid when safer effective alternatives exist
Self-check
- When are Fluoroquinolones especially useful?
selected UTI, GI + respiratory disease.
Drugs in this class (5)
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