Estrogens
- Replace or supplement estrogen signaling
- Menopause symptoms + contraception are major uses
- Systemic estrogen treats vasomotor symptoms
- Local vaginal estrogen treats GSM/VVA
- VTE/stroke risks depend on route + patient
- Intact uterus needs endometrial protection
- Avoid systemic estrogen in estrogen-sensitive cancer
Class at a glance
- Replace or supplement estrogen signaling
Clinical role
- Menopause symptoms + contraception are major uses
- Systemic estrogen treats vasomotor symptoms
Other clinical roles
- Local vaginal estrogen treats GSM/VVA
- Intact uterus needs endometrial protection
Safety / monitoring
- VTE/stroke risks depend on route + patient
- Avoid systemic estrogen in estrogen-sensitive cancer
Self-check
- What does an intact uterus require with estrogen therapy?
Endometrial protection. - Which estrogen route treats GSM/VVA locally?
Vaginal.
Drugs in this class (10)
All drug classes · Open Estrogens in the interactive console ↗