Endocannabinoids
- Endogenous cannabinoid signaling molecules
- Anandamide + 2-AG are key examples
- Synthesized on demand rather than vesicle-stored
- Often act retrogradely at CB1
- Regulate appetite, pain, stress + synapses
- Rapid enzymatic breakdown limits duration
Class at a glance
- Endogenous cannabinoid signaling molecules
Practical pearls
- Anandamide + 2-AG are key examples
Members / distinctions
- Synthesized on demand rather than vesicle-stored
- Often act retrogradely at CB1
Clinical role
- Regulate appetite, pain, stress + synapses
- Rapid enzymatic breakdown limits duration
Drugs in this class (2)
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