Endocannabinoids
- Endogenous cannabinoid signaling molecules
- Anandamide + 2-AG are key examples
- Synthesized on demand rather than vesicle-stored
- Often act retrogradely at CB1
- Regulate appetite, pain, stress + synapses
- Rapid enzymatic breakdown limits duration
Class at a glance
- Endogenous cannabinoid signaling molecules
Practical pearls
- Anandamide + 2-AG are key examples
Members / distinctions
- Synthesized on demand rather than vesicle-stored
- Often act retrogradely at CB1
Clinical role
- Regulate appetite, pain, stress + synapses
- Rapid enzymatic breakdown limits duration
Self-check
- How are endocannabinoids supplied rather than stored in vesicles?
Synthesized on demand. - At which receptor do endocannabinoids often act retrogradely?
CB1.
Drugs in this class (2)
All drug classes · Open Endocannabinoids in the interactive console ↗