Antineoplastics (cytotoxic chemotherapy)
- Directly injure dividing cells
- Includes alkylators, antimetabolites + more
- Myelosuppression is a frequent dose limit
- Nausea, alopecia + mucositis vary by regimen
- Curative potential remains high in some cancers
- Regimens matter more than single-drug labels
Class at a glance
- Directly injure dividing cells
Members / distinctions
- Includes alkylators, antimetabolites + more
- Regimens matter more than single-drug labels
Clinical role
- Nausea, alopecia + mucositis vary by regimen
- Curative potential remains high in some cancers
Practical pearls
- Myelosuppression is a frequent dose limit
Self-check
- Which groups are included in Antineoplastics (cytotoxic chemotherapy)?
Alkylators, antimetabolites + more. - What frequently limits cytotoxic chemotherapy dosing?
Myelosuppression.
Drugs in this class (16)
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