Antimycobacterials
- Treat tuberculosis or related mycobacteria
- TB requires multidrug therapy
- Resistance emerges rapidly with monotherapy
- Rifamycins drive many CYP/P-gp interactions
- Hepatic, optic + neuropathy risks vary
- Duration is longer than routine antibiotics
Class at a glance
- Treat tuberculosis or related mycobacteria
Pharmacology
- Rifamycins drive many CYP/P-gp interactions
Members / distinctions
- TB requires multidrug therapy
- Resistance emerges rapidly with monotherapy
- Duration is longer than routine antibiotics
Safety / monitoring
- Hepatic, optic + neuropathy risks vary
Self-check
- Which antimycobacterial subgroup drives many CYP/P-gp interactions?
Rifamycins.
Drugs in this class (8)
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