Urticaria
- 2nd-generation H1 antihistamine is first-line
- Increase dose for persistent chronic urticaria
- Omalizumab for antihistamine-refractory chronic disease
- Avoid chronic systemic steroids
- Epinephrine only when anaphylaxis is present
- Search for a cause only when history/exam suggests one
Use at a glance
- 2nd-generation H1 antihistamine is first-line
Escalation / refractory disease
- Omalizumab for antihistamine-refractory chronic disease
Practical pearls
- Increase dose for persistent chronic urticaria
Choosing treatment
- Epinephrine only when anaphylaxis is present
- Search for a cause only when history/exam suggests one
Safety / pitfalls
- Avoid chronic systemic steroids
Self-check
- What is first-line medication treatment for urticaria?
A second-generation H1 antihistamine.
- What is used for antihistamine-refractory chronic urticaria?
Omalizumab.
Drugs used for this (4)
All clinical uses · Open the interactive console ↗
