Thrombolysis
- Fibrinolytic therapy dissolves acute thrombus
- Use only in time-sensitive selected indications
- Ischemic stroke requires imaging/eligibility screening
- STEMI uses lysis mainly when timely PCI unavailable
- Massive PE with shock may warrant thrombolysis
- Intracranial bleeding is the major feared toxicity
Use at a glance
- Fibrinolytic therapy dissolves acute thrombus
Practical pearls
- Ischemic stroke requires imaging/eligibility screening
Choosing treatment
- Use only in time-sensitive selected indications
- STEMI uses lysis mainly when timely PCI unavailable
- Massive PE with shock may warrant thrombolysis
Other practical pearls
- Intracranial bleeding is the major feared toxicity
Self-check
- When is thrombolysis used?
Only in time-sensitive selected indications.
- What is required before thrombolysis for ischemic stroke?
Imaging + eligibility screening.
- What is the major feared toxicity of thrombolysis?
Intracranial bleeding.
Drugs used for this (2)
All clinical uses · Open the interactive console ↗
