Tardive dyskinesia (TD)
- Confirm persistent involuntary movements
- Reduce causative dopamine blocker if feasible
- VMAT2 inhibitor is first-line drug therapy
- valbenazine or deutetrabenazine
- Do not simply add chronic anticholinergic
- Anticholinergics may worsen classic TD
- Monitor serially with structured movement exam
Use at a glance
- Confirm persistent involuntary movements
Treatment options
- VMAT2 inhibitor is first-line drug therapy
- valbenazine or deutetrabenazine
- Anticholinergics may worsen classic TD
Choosing treatment
- Reduce causative dopamine blocker if feasible
Monitoring / follow-up
- Do not simply add chronic anticholinergic
- Monitor serially with structured movement exam
Self-check
- What is first-line drug therapy for TD?
A VMAT2 inhibitor. - Can anticholinergics worsen classic TD?
Yes.
Drugs used for this (2)
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