Small cell lung cancer (SCLC)
- Limited-stage: platinum/etoposide + thoracic radiation
- Extensive-stage: platinum/etoposide + immunotherapy
- SCLC is initially chemo-sensitive but relapse is common
- Brain surveillance/prevention strategy is stage/context dependent
- Relapse uses lurbinectedin/topotecan or other options
- Smoking cessation and symptom palliation remain important
Use at a glance
- Limited-stage: platinum/etoposide + thoracic radiation
Practical pearls
- SCLC is initially chemo-sensitive but relapse is common
Other practical pearls
- Relapse uses lurbinectedin/topotecan or other options
- Smoking cessation and symptom palliation remain important
Monitoring / follow-up
- Extensive-stage: platinum/etoposide + immunotherapy
- Brain surveillance/prevention strategy is stage/context dependent
Self-check
- What is used for limited-stage SCLC?
Platinum/etoposide + thoracic radiation.
- What is used for extensive-stage SCLC?
Platinum/etoposide + immunotherapy.
Drugs used for this (1)
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