SARS-CoV-2 / COVID-19
- Outpatient treatment is for high-risk disease
- Nirmatrelvir/ritonavir preferred when usable
- Remdesivir is an effective early IV alternative
- Start antiviral treatment early
- Check ritonavir DDIs before prescribing
- Steroid is for oxygen need—not mild disease
- Immunomodulators are for severe inflammation
Use at a glance
- Outpatient treatment is for high-risk disease
Treatment options
- Remdesivir is an effective early IV alternative
- Start antiviral treatment early
Choosing treatment
- Nirmatrelvir/ritonavir preferred when usable
- Steroid is for oxygen need—not mild disease
- Immunomodulators are for severe inflammation
Practical pearls
- Check ritonavir DDIs before prescribing
Self-check
- When should COVID antiviral treatment start?
Early. - What is checked before prescribing ritonavir?
Drug interactions.
Drugs used for this (3)
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