Salicylate poisoning
- Avoid intubation if possible; ventilation is compensatory
- Give IV sodium bicarbonate
- alkalinize serum + urine
- Replete potassium to permit urine alkalinization
- Serial levels + acid-base status guide treatment
- Dialysis for severe CNS/lung/acidosis toxicity
Use at a glance
- Avoid intubation if possible; ventilation is compensatory
Practical pearls
- Give IV sodium bicarbonate
- alkalinize serum + urine
Choosing treatment
- Replete potassium to permit urine alkalinization
- Serial levels + acid-base status guide treatment
Other practical pearls
- Dialysis for severe CNS/lung/acidosis toxicity
Self-check
- Why avoid intubation if possible in salicylate poisoning?
Ventilation is compensatory. - What is a core drug treatment for salicylate poisoning?
IV sodium bicarbonate.
Drugs used for this (1)
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