Restless legs syndrome (RLS)
- Check iron first; replace if stores are low
- Remove aggravators when feasible
- Gabapentin/pregabalin often preferred drugs
- Dopamine agonists work but cause augmentation
- Severe refractory disease may need opioid therapy
- Treat sleep apnea if present
- Avoid chronic sedating antihistamine triggers
Use at a glance
- Check iron first; replace if stores are low
Choosing treatment
- Remove aggravators when feasible
Treatment options
- Gabapentin/pregabalin often preferred drugs
- Dopamine agonists work but cause augmentation
Escalation / refractory disease
- Severe refractory disease may need opioid therapy
- Treat sleep apnea if present
Safety / pitfalls
- Avoid chronic sedating antihistamine triggers
Self-check
- What should be checked in Restless legs syndrome (RLS)?
iron first; replace if stores are low.
- What should be treated in Restless legs syndrome (RLS)?
sleep apnea if present.
Drugs used for this (5)
All clinical uses · Open the interactive console ↗
