Polycythemia vera (PV)
- Keep hematocrit <45%
- Phlebotomy + low-dose aspirin for most
- Cytoreduce higher-risk disease
- hydroxyurea or interferon common
- JAK inhibitor for selected resistant/intolerant disease
- Manage thrombosis risk aggressively
Use at a glance
- Keep hematocrit <45%
Practical pearls
- Phlebotomy + low-dose aspirin for most
Choosing treatment
- JAK inhibitor for selected resistant/intolerant disease
Other practical pearls
- Cytoreduce higher-risk disease
- hydroxyurea or interferon common
- Manage thrombosis risk aggressively
Self-check
- What is the PV hematocrit target?
<45% - What is used for most PV patients?
Phlebotomy + low-dose aspirin.
Drugs used for this (2)
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