Parkinsonism (antipsychotic-induced)
- Reduce dose or switch antipsychotic if feasible
- Amantadine is useful, especially in older adults
- Antimuscarinics can help younger patients short-term
- Avoid chronic antimuscarinic burden when possible
- Levodopa usually conflicts with antipsychotic goal
- Distinguish drug-induced disease from idiopathic PD
Use at a glance
- Reduce dose or switch antipsychotic if feasible
Treatment options
- Amantadine is useful, especially in older adults
- Antimuscarinics can help younger patients short-term
- Distinguish drug-induced disease from idiopathic PD
Other treatment options
- Levodopa usually conflicts with antipsychotic goal
Safety / pitfalls
- Avoid chronic antimuscarinic burden when possible
Self-check
- What long-term burden is avoided in antipsychotic parkinsonism when possible?
Chronic antimuscarinic burden when possible. - What antipsychotic adjustment may help parkinsonism, if feasible?
Reduce the dose or switch.
Drugs used for this (3)
All clinical uses · Open Parkinsonism (antipsychotic-induced) in the interactive console ↗