Obsessive-compulsive disorder (OCD)
- ERP-focused CBT + serotonin reuptake block
- SSRIs often need higher-end doses
- Clomipramine effective but less tolerable
- Trial must be longer than for depression
- Partial response → optimize + ERP
- Resistant: antipsychotic augmentation
- aripiprazole/risperidone best supported
Use at a glance
- ERP-focused CBT + serotonin reuptake block
Practical pearls
- SSRIs often need higher-end doses
- Clomipramine effective but less tolerable
Other practical pearls
- Trial must be longer than for depression
- Partial response → optimize + ERP
Treatment options
- Resistant: antipsychotic augmentation
- aripiprazole/risperidone best supported
Self-check
- What follows a partial OCD response?
Optimize + ERP. - How long should an OCD trial be relative to depression?
Longer.
Drugs used for this (6)
All clinical uses · Open Obsessive-compulsive disorder (OCD) in the interactive console ↗