Neutropenia — prevention/treatment
- G-CSF prevents/treats selected chemotherapy neutropenia
- Primary prophylaxis depends on febrile-neutropenia risk
- Febrile neutropenia → immediate empiric antibiotics
- Pegfilgrastim offers long-acting prophylaxis
- Severe chronic neutropenia may also use G-CSF
- Treat the cause and avoid unnecessary routine use
Use at a glance
- G-CSF prevents/treats selected chemotherapy neutropenia
Treatment options
- Febrile neutropenia → immediate empiric antibiotics
- Pegfilgrastim offers long-acting prophylaxis
Practical pearls
- Severe chronic neutropenia may also use G-CSF
Safety / pitfalls
- Primary prophylaxis depends on febrile-neutropenia risk
- Treat the cause and avoid unnecessary routine use
Self-check
- What determines primary prophylaxis for chemotherapy-associated neutropenia?
Febrile-neutropenia risk. - What urgently treats febrile neutropenia?
Immediate empiric antibiotics.
Drugs used for this (2)
All clinical uses · Open Neutropenia — prevention/treatment in the interactive console ↗