Myasthenia gravis (MG)
- Pyridostigmine gives rapid symptomatic relief
- Immunotherapy if symptoms remain significant
- steroid ± steroid-sparing agent
- Thymectomy for appropriate AChR+ generalized MG
- Biologic/FcRn/complement drugs if refractory
- Crisis → IVIG/PLEX + respiratory support
- Avoid drugs that worsen NM transmission
Use at a glance
- Pyridostigmine gives rapid symptomatic relief
Practical pearls
- Thymectomy for appropriate AChR+ generalized MG
Escalation / refractory disease
- Immunotherapy if symptoms remain significant
- steroid ± steroid-sparing agent
- Biologic/FcRn/complement drugs if refractory
Safety / pitfalls
- Crisis → IVIG/PLEX + respiratory support
- Avoid drugs that worsen NM transmission
Self-check
- What is recommended for Crisis in Myasthenia gravis (MG)?
IVIG/PLEX + respiratory support.
- What should generally be avoided in Myasthenia gravis (MG)?
drugs that worsen NM transmission.
Drugs used for this (1)
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