Multiple sclerosis (MS) — walking impairment
- Dalfampridine can improve walking speed in selected patients
- Benefit is symptomatic—not disease-modifying
- Avoid with seizure history or significant renal impairment
- Physical therapy/assistive devices remain important
- Stop if no meaningful functional benefit
- Treat spasticity/fatigue contributors separately
Use at a glance
- Dalfampridine can improve walking speed in selected patients
Practical pearls
- Benefit is symptomatic—not disease-modifying
Treatment options
- Physical therapy/assistive devices remain important
- Treat spasticity/fatigue contributors separately
Safety / pitfalls
- Avoid with seizure history or significant renal impairment
- Stop if no meaningful functional benefit
Self-check
- What should be stopped immediately in Multiple sclerosis (MS) — walking impairment?
if no meaningful functional benefit.
- What should be treated in Multiple sclerosis (MS) — walking impairment?
spasticity/fatigue contributors separately.
Drugs used for this (1)
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