Methanol poisoning
- Fomepizole blocks toxic alcohol metabolism
- Give folinic/folic acid to enhance formate metabolism
- Correct severe metabolic acidosis
- Hemodialysis for severe acidosis/visual toxicity/high level
- Visual symptoms are a major warning sign
- Treat before confirmatory level if suspicion is strong
Use at a glance
- Fomepizole blocks toxic alcohol metabolism
Choosing treatment
- Treat before confirmatory level if suspicion is strong
Practical pearls
- Give folinic/folic acid to enhance formate metabolism
Other practical pearls
- Correct severe metabolic acidosis
Clinical pearls
- Hemodialysis for severe acidosis/visual toxicity/high level
- Visual symptoms are a major warning sign
Self-check
- When is methanol poisoning treated before a confirmatory level?
When suspicion is strong. - What does fomepizole block in methanol poisoning?
Toxic alcohol metabolism.
Drugs used for this (1)
All clinical uses · Open Methanol poisoning in the interactive console ↗