Major depressive disorder (MDD) with acute suicidal ideation/behavior
- Safety setting + lethal-means reduction first
- Treat the underlying depression concurrently
- Esketamine can rapidly reduce depressive symptoms
- It has NOT proven suicide-prevention benefit
- Lithium lowers long-term suicide risk in mood illness
- ECT is rapid/effective for severe suicidal depression
- Medication never replaces safety planning
Use at a glance
- Safety setting + lethal-means reduction first
Practical pearls
- Treat the underlying depression concurrently
- Esketamine can rapidly reduce depressive symptoms
- It has NOT proven suicide-prevention benefit
Other practical pearls
- ECT is rapid/effective for severe suicidal depression
Clinical pearls
- Lithium lowers long-term suicide risk in mood illness
- Medication never replaces safety planning
Self-check
- What comes first in MDD with acute suicidal ideation/behavior?
Safety setting + lethal-means reduction.
- What rapid treatment is effective for severe suicidal depression?
ECT.
Drugs used for this (1)
All clinical uses · Open the interactive console ↗
