Hypertrophic cardiomyopathy (HCM, obstructive)
- Treat symptoms + LV outflow obstruction
- Beta blocker is common first drug
- Verapamil/diltiazem if beta blocker unsuitable
- Persistent symptoms → cardiac myosin inhibitor
- Severe refractory obstruction → septal reduction
- Avoid excessive preload/afterload reduction
Use at a glance
- Treat symptoms + LV outflow obstruction
Treatment options
- Beta blocker is common first drug
- Persistent symptoms → cardiac myosin inhibitor
Escalation / refractory disease
- Verapamil/diltiazem if beta blocker unsuitable
- Severe refractory obstruction → septal reduction
Safety / pitfalls
- Avoid excessive preload/afterload reduction
Self-check
- What should be treated in Hypertrophic cardiomyopathy (HCM, obstructive)?
symptoms + LV outflow obstruction.
- What should generally be avoided in Hypertrophic cardiomyopathy (HCM, obstructive)?
excessive preload/afterload reduction.
Drugs used for this (2)
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