Hypercalcemia
- Treat cause + severity
- Severe symptomatic disease → IV saline
- Calcitonin lowers Ca quickly but tachyphylaxes
- Bisphosphonate/denosumab gives sustained effect
- Glucocorticoid for vitamin-D–mediated causes
- Dialysis for selected severe renal/refractory cases
Use at a glance
Practical pearls
- Calcitonin lowers Ca quickly but tachyphylaxes
- Bisphosphonate/denosumab gives sustained effect
Escalation / refractory disease
- Severe symptomatic disease → IV saline
- Dialysis for selected severe renal/refractory cases
Other practical pearls
- Glucocorticoid for vitamin-D–mediated causes
Self-check
- What should be treated in Hypercalcemia?
cause + severity.
- What is recommended for Severe symptomatic disease in Hypercalcemia?
IV saline.
Drugs used for this (1)
All clinical uses · Open the interactive console ↗
