Hyperaldosteronism
- Unilateral disease → adrenalectomy when appropriate
- Bilateral disease → mineralocorticoid receptor antagonist
- Spironolactone is common; eplerenone is more selective
- Correct hypokalemia + control BP
- Confirm diagnosis before definitive subtype workup
- Monitor K+ and kidney function during therapy
Use at a glance
- Unilateral disease → adrenalectomy when appropriate
Practical pearls
- Confirm diagnosis before definitive subtype workup
Other practical pearls
- Bilateral disease → mineralocorticoid receptor antagonist
- Spironolactone is common; eplerenone is more selective
- Correct hypokalemia + control BP
Monitoring / follow-up
- Monitor K+ and kidney function during therapy
Self-check
- What is used for bilateral hyperaldosteronism?
A mineralocorticoid receptor antagonist. - What is monitored during hyperaldosteronism therapy?
K+ and kidney function.
Drugs used for this (1)
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