Growth hormone deficiency
- Confirm biochemical deficiency in the proper context
- Recombinant growth hormone is replacement therapy
- Titrate to IGF-1 and clinical response
- Children: growth velocity is a major endpoint
- Adults: monitor edema, glucose + joint symptoms
- Do not use GH for nonspecific fatigue/anti-aging
Use at a glance
- Confirm biochemical deficiency in the proper context
Treatment options
- Recombinant growth hormone is replacement therapy
Practical pearls
- Titrate to IGF-1 and clinical response
- Children: growth velocity is a major endpoint
Monitoring / follow-up
- Adults: monitor edema, glucose + joint symptoms
- Do not use GH for nonspecific fatigue/anti-aging
Self-check
- What must precede growth-hormone replacement?
Biochemical deficiency in the proper context. - What guides growth-hormone titration?
IGF-1 and clinical response.
Drugs used for this (1)
All clinical uses · Open Growth hormone deficiency in the interactive console ↗