Glioblastoma
- Maximal safe resection when feasible
- Radiation + temozolomide is standard backbone
- Continue adjuvant temozolomide after chemoradiation
- Tumor-treating fields can be added in selected patients
- MGMT methylation predicts temozolomide benefit
- Recurrence therapy is individualized; cure remains uncommon
Use at a glance
- Maximal safe resection when feasible
Practical pearls
- Radiation + temozolomide is standard backbone
Treatment options
- Continue adjuvant temozolomide after chemoradiation
- MGMT methylation predicts temozolomide benefit
- Recurrence therapy is individualized; cure remains uncommon
Choosing treatment
- Tumor-treating fields can be added in selected patients
Self-check
- What is a key treatment approach for Glioblastoma?
Radiation + temozolomide is standard backbone.
Drugs used for this (2)
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