Ethylene glycol poisoning
- Fomepizole blocks toxic alcohol metabolism
- Correct acidosis + electrolyte abnormalities
- Give thiamine/pyridoxine as adjuncts
- Hemodialysis for severe acidosis, AKI or high burden
- Osmol gap can disappear late
- Treat on strong suspicion—do not await final level
Use at a glance
- Fomepizole blocks toxic alcohol metabolism
Practical pearls
- Correct acidosis + electrolyte abnormalities
- Osmol gap can disappear late
Other practical pearls
- Hemodialysis for severe acidosis, AKI or high burden
Safety / pitfalls
- Give thiamine/pyridoxine as adjuncts
- Treat on strong suspicion—do not await final level
Self-check
- What should be treated in Ethylene glycol poisoning?
on strong suspicion—do not await final level.
- What does Fomepizole block in Ethylene glycol poisoning?
toxic alcohol metabolism.
Drugs used for this (1)
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