Ethylene glycol poisoning
- Fomepizole blocks toxic alcohol metabolism
- Correct acidosis + electrolyte abnormalities
- Give thiamine/pyridoxine as adjuncts
- Hemodialysis for severe acidosis, AKI or high burden
- Osmol gap can disappear late
- Treat on strong suspicion—do not await final level
Use at a glance
- Fomepizole blocks toxic alcohol metabolism
Practical pearls
- Correct acidosis + electrolyte abnormalities
- Osmol gap can disappear late
Other practical pearls
- Hemodialysis for severe acidosis, AKI or high burden
Safety / pitfalls
- Give thiamine/pyridoxine as adjuncts
- Treat on strong suspicion—do not await final level
Self-check
- Await the final level with strongly suspected ethylene glycol poisoning?
No; treat on strong suspicion. - What does fomepizole block?
Toxic alcohol metabolism.
Drugs used for this (1)
All clinical uses · Open Ethylene glycol poisoning in the interactive console ↗