Essential thrombocythemia (ET)
- Risk-stratify thrombosis/bleeding
- Low-dose aspirin for many patients
- Cytoreduce higher-risk disease
- hydroxyurea is common first-line
- Interferon is useful in younger/pregnant patients
- Extreme thrombocytosis can cause acquired vWD
Use at a glance
- Risk-stratify thrombosis/bleeding
Practical pearls
- Low-dose aspirin for many patients
- Extreme thrombocytosis can cause acquired vWD
Other practical pearls
- Interferon is useful in younger/pregnant patients
Treatment options
- Cytoreduce higher-risk disease
- hydroxyurea is common first-line
Self-check
- Which risks guide ET stratification?
Thrombosis and bleeding. - What can extreme thrombocytosis cause in ET?
Acquired von Willebrand disease.
Drugs used for this (1)
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