Endometriosis
- NSAID for pain + hormonal suppression for disease symptoms
- Combined contraceptive or progestin is common first-line
- GnRH agonist/antagonist for persistent symptoms
- Add-back therapy reduces hypoestrogenic toxicity
- Surgery for refractory pain, endometrioma or fertility goals
- Recurrence is common without ongoing suppression
Use at a glance
- NSAID for pain + hormonal suppression for disease symptoms
Escalation / refractory disease
- Combined contraceptive or progestin is common first-line
- Surgery for refractory pain, endometrioma or fertility goals
Practical pearls
- GnRH agonist/antagonist for persistent symptoms
- Recurrence is common without ongoing suppression
Treatment options
- Add-back therapy reduces hypoestrogenic toxicity
Self-check
- When is surgery used for endometriosis?
For refractory pain, endometrioma or fertility goals. - What does add-back therapy reduce in endometriosis treatment?
Hypoestrogenic toxicity.
Drugs used for this (4)
All clinical uses · Open Endometriosis in the interactive console ↗